BEYOND ONE SIZE · EDUCATIONAL ATLAS

Methylation Patterns Atlas

Explore nine interconnected biochemical patterns across folate metabolism, remethylation, transsulfuration, methionine, SAM, SAH, and organ-related regulation.

Hover over a pattern to highlight the related pathway. Select it to open the full atlas entry.

PATTERN 01 Folate-Limited Remethylation OPEN ↗ PATTERN 02 B12 Remethylation & Methylfolate Trap OPEN ↗ PATTERN 03 Riboflavin-Sensitive MTHFR 677TT OPEN ↗ PATTERN 04 Choline, Betaine & BHMT Remethylation OPEN ↗ PATTERN 05 Accelerated or Preferential Transsulfuration OPEN ↗
Simplified methylation and one-carbon metabolism pathway map A simplified map of folate-dependent remethylation, the methionine cycle, BHMT remethylation, transsulfuration, cerebral folate delivery, and liver-related regulation. 5,10-MTHF 5-MTHF B12 / MTR Methionine SAM SAH Homocysteine BHMT Choline / Betaine Cystathionine CNS Liver
ATLAS ORIENTATION Nine patterns, one connected system Hover over an atlas entry to highlight the related pathway and see a concise interpretation note.
PATTERN 06 Cerebral Folate Deficiency & Impaired CNS Delivery OPEN ↗ PATTERN 09 Hepatic Methionine & SAM Homeostasis OPEN ↗
APPLIES ACROSS THE ATLAS Interpretation Modifiers Factors that may alter, mimic, obscure, or complicate methylation-related patterns. Organ function · Nutrient status · Medications · Supplements · Sample conditions · Analytical limitations EXPLORE ↗
BEYOND ONE SIZE · EDUCATIONAL ATLAS

Methylation Patterns Atlas

Explore nine interconnected biochemical patterns across folate metabolism, remethylation, transsulfuration, methionine, SAM, SAH, and organ-related regulation.

Hover over a pattern to highlight the related pathway. Select it to open the full atlas entry. Select a pattern to open the full atlas entry.

Simplified methylation and one-carbon metabolism pathway map A simplified map of folate-dependent remethylation, the methionine cycle, BHMT remethylation, transsulfuration, cerebral folate delivery, and liver-related regulation. 5,10-MTHF 5-MTHF B12 / MTR Methionine SAM SAH Homocysteine BHMT Choline / Betaine Cystathionine CNS Liver
ATLAS ORIENTATION Nine patterns, one connected system Hover over an atlas entry to highlight the related pathway and see a concise interpretation note.
APPLIES ACROSS THE ATLASInterpretation ModifiersFactors that may alter, mimic, obscure, or complicate methylation-related patterns. Organ function · Nutrient status · Medications · Supplements · Sample conditions · Analytical limitations EXPLORE ↗
BEYOND ONE SIZE · EDUCATIONAL ATLAS

Methylation Patterns Atlas

Explore nine interconnected biochemical patterns across folate metabolism, remethylation, transsulfuration, methionine, SAM, SAH, and organ-related regulation.

Select a pattern to open the full atlas entry.

Simplified methylation pathway map A mobile orientation map showing folate-dependent remethylation, the methionine cycle, BHMT remethylation, transsulfuration, cerebral folate delivery, and liver-related regulation. 5-MTHFfolate donor B12 / MTRremethylation Methioninesubstrate supply 5,10-MTHFMTHFR SAMmethyl donor SAHmethylationproduct Homocysteinebranch point BHMT CholineBetaine Cystathioninesulfur flux CNS Liver

A simplified orientation map. Each atlas entry explains a specific pattern, its markers, possible confounders, and interpretation limits.

APPLIES ACROSS THE ATLAS Interpretation Modifiers Factors that may alter, mimic, obscure, or complicate methylation-related patterns. EXPLORE ↗
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